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Synchrovit Clinical Data

Clinical Evaluations of Key Synchrovit Formula.

A Clinical Assessment of the 'anti wrinkle' activity of Synchrovit® using polarized light cameras

University of Pavia carried out by Professors Richelmi and Berte and Dr Mainardi

20 female subject aged between18 and 45 years were selected ont he basis of health, lack of any skin diseases, not on current medication, with a regular daily routine and no history of atopy

Synchrovit® was applied evenly as according to the manufacturers instructions to selected areas of the face as described by the instruction sheet given to the volunteer. The first application was carried out in the laboratory for demonstration purposes.

The following initial basal measurements were

• Skin Compactness
• Skin Colour
• Presence of Flaky Skin

At this time a polarized light camera was used to take 20 photographs of the skin.

Measurements were then taken by the experimenter in the laboratory at intervals of 7, 15, 30 and 60 days.

Any variation in the test parameters were included in the summary charts and displayed graphically. The results were also displayed using 3 dimensional pictures of the cutis

The measurement parameters were described and assigned values as follows

Compactness of Skin	Score
Not Compact (cutis with very low degree of elasticity)	-4
Insufficient Compactness (cutis with a low degree of elasticity)	-2
Compact	0
Very Compact Cutis with good degree of elasticity	2

 

Skin Colour	Score
Vary Fair, Pale	-2
Fair	0
Rosy	2

 

Presence of Flaky Skin (scales)	Score
Numerous Large Scales	-4
Medium Scales	-2
Small Scales	0
No Desquamation	2

Change in Wrinkle Appearance	Score
No Variation	-2
Slight Variation	0
Significant Variation	2

 

Results

Compactness of Skin	Average Value
Time = 0 days	-1.4
Time = 7 days	-1.4
Time = 14 days	-1.2
Time = 30 days	-0.2
Time = 60 days	0.3

Skin Colour	Average Value
Time = 0 days	-0.6
Time = 7 days	-0.6
Time = 14 days	-0.6
Time = 30 days	0.4
Time = 60 days	1.0

Flaky Skin	Average Value
Time = 0 days	-1.2
Time = 7 days	0.1
Time = 14 days	0.7
Time = 30 days	0.9
Time = 60 days	1.1

Wrinkle Appearance Change	Average Value
Time = 0 days	0
Time = 7 days	0.2
Time = 14 days	0.6
Time = 30 days	1.2
Time = 60 days	1.5